Almax (almagate) / Almirall - LARVOL DELTA

Construction of a ratiometric turn-on fluorescent probe based on amino acid skeleton for specific detection of Al3+ ions in environmental and biological system. (PubMed, Spectrochim Acta A Mol Biomol Spectrosc) - "Furthermore, NHO's multifaceted practical applications in detecting Al3+ ions were explored, including tests in real water samples, commercially available almagate suspension and applications on test paper...Additionally, NHO also exhibited promising bioimaging capabilities in PK-15 cells. These inventions highlighted that NHO was a useful tool for the detection of Al3+ in both environmental and living systems."

Journal

Method of precise optical crystal alignment by tilting the diamond anvil cell. (PubMed, J Appl Crystallogr) - "It enables highly accurate crystal alignment within instruments with a Boehler-Almax DAC design, achieving precision better than 0.02 mm easily...This method employs Snell's law, which relates the angles of incidence and refraction of light passing through different media to estimate the crystal position within the DAC by measuring the apparent transverse dis-placement of the crystal image at various viewing angles after rotating the DAC by 180°. This information allows for fine-tuning of the crystal alignment within the DAC, ensuring optimal conditions for high-pressure diffraction experiments."

Journal

Optical nonreciprocity in multilayer nanoisland systems of [Ag--AlO]. (PubMed, J Phys Condens Matter) - "We study the effect of optical nonreciprocity in [Ag--Almax ≈ 7°. We suggest that a possible mechanism for the optical nonreciprocity effect in these structures can be related to the excitation of localized plasmons in Ag islands. We show that Δω essentially depends on the interlayer and intralayer interaction between Ag layers in multilayer structures and is suppressed in the case of strong intralayer and interlayer interaction of plasma oscillations."

Journal

Combining Liquid Oral Drugs with Thickener: Compatibility and Changes in Viscosity. (PubMed, Dysphagia) - "Three drugs (almagate, ibuprofen, and macrogol) were found to be physically incompatible with the thickener and should not be mixed. Viscosity measurements indicated that clarithromycin and plantago ovata increased the viscosity of the mixture and required lower amount to achieve the target textures (110 cP, 590 cP, and 2620 cP for 7 g, 10 g, and 12 g in drug-free samples, respectively), whereas another subset reduced viscosity and required more thickener. This proved very relevant for acetylcysteine, amoxicillin, calcifediol, ferrous gluconate, fosfomycin, lactitol, lactulose, mepifiline, paracetamol, rivastigmine, sertraline, and tramadol. Measurements were below 1750 cP. Awareness of how each drug behaves when combined with thickeners is essential to avoid potential complications in OD."

Journal • Gastrointestinal Disorder

Ethanol induces necroptosis in gastric epithelial cells in vitro. (PubMed, J Food Biochem) - "Considering the unique distribution of ethanol on gastric mucosa, it is worthwhile to explore the specific cell death pattern of gastric epithelial cells under high-concentration ethanol treatment. Further investigation of the mechanisms of alcoholic gastric diseases would provide potential therapeutic strategies for the treatment of acute alcoholic gastric diseases as well as other acute alcoholic diseases."

Journal • Preclinical • Addiction (Opioid and Alcohol) • Gastrointestinal Disorder • Hepatology • RIPK1

Lack of almagate interference in breath test results for Helicobacter pylori diagnosis (Almatest study). (PubMed, Gastroenterol Hepatol) - "Taking almagate has minimal or no interference in the result of UBT for the diagnosis of H. pylori infection. It can therefore be used in the weeks prior to a UBT."

Journal • Dyspepsia • Gastrointestinal Disorder • Infectious Disease

Effectiveness of Almagate in gastroesophageal reflux disease: a post-hoc analysis of a randomized cross-over double-blind study. (PubMed, Rev Esp Enferm Dig) - "Not applicable."

Clinical • Journal • Retrospective data • Gastroenterology • Gastroesophageal Reflux Disease

[VIRTUAL] ALMAGATE SUSPENSION SPARING TO TREAT THE ENDOSCOPIC SUBMOCOSAL DISSECTION-INDUCED GASTRIC ULCERS: A SINGLE-CENTER RANDOMIZED STUDY (UEGW 2020) - "Almagate suspension spraying is safe and effective in the treatment of upper gastrointestinal ESD postoperative ulcer, which can also relieve the postoperative pain."

Clinical • Gastric Cancer • Gastrointestinal Cancer • Oncology • Pain • Peptic Ulcer • Solid Tumor

[VIRTUAL] ALMAGATE SUSPENSION SPARING TO TREAT THE ENDOSCOPIC SUBMOCOSAL DISSECTION-INDUCED GASTRIC ULCERS: A SINGLE-CENTER RANDOMIZED STUDY (UEGW 2020) - "Almagate suspension spraying is safe and effective in the treatment of upper gastrointestinal ESD postoperative ulcer, which can also relieve the postoperative pain."

Clinical • Gastric Cancer • Gastrointestinal Cancer • Oncology • Pain • Peptic Ulcer • Solid Tumor

[VIRTUAL] ALMAGATE SUSPENSION SPARING TO TREAT THE ENDOSCOPIC SUBMOCOSAL DISSECTION-INDUCED GASTRIC ULCERS: A SINGLE-CENTER RANDOMIZED STUDY (UEGW 2020) - "Almagate suspension spraying is safe and effective in the treatment of upper gastrointestinal ESD postoperative ulcer, which can also relieve the postoperative pain."

Clinical • Gastric Cancer • Gastrointestinal Cancer • Oncology • Pain • Peptic Ulcer • Solid Tumor