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- LARVOL DELTA
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May 30, 2020
[VIRTUAL] Efficacy of zinc on human hepatic copper uptake depending on zinc type and dose regimen quantified with 64-CuCl2 PET/CTscan
(EASL-ILC-I 2020)
- "Hepatic copper uptake was determined with 64-Cu PET/CT scans before and after four weeks of treatment with either Zn-ac 50 mg x 3 daily, Zn-ac 150 mg x 1 daily or zinc gluconate (Zn-glu) 150 mg x 1 daily... The effect of zinc treatment on hepatic copper uptake is highly variable but quantifiable by 64-Cu PET/CT scan, indicating that efficacy evaluation by 64 Cu-PET/CT is advisable in WD. Zinc thrice daily was not significantly different than once daily as long as the zinc type was Zn-ac."
Clinical • Metabolic Disorders • Movement Disorders
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