ASKG712 / Aosaikang Pharma, AffaMed Therap - LARVOL DELTA

Phase 1 Study of ASKG712 (Anti-VEGF-A/Ang-2 Bispecific Antibody) for Diabetic Macular Edema (DME) (ARVO 2025) - P1 | "Layman Abstract (optional): Provide a 50-200 word description of your work that non-scientists can understand. Describe the big picture and the implications of your findings, not the study itself and the associated details."

P1 data • Diabetic Macular Edema • Diabetic Retinopathy • Ophthalmology • Retinal Disorders

Safety, Tolerability and Efficacy of Intravitreal AM712 for Neovascular Age-Related Macular Degeneration (CONQUER) (ARVO 2025) - "Layman Abstract (optional): Provide a 50-200 word description of your work that non-scientists can understand. Describe the big picture and the implications of your findings, not the study itself and the associated details."

Clinical • Age-related Macular Degeneration • Macular Degeneration • Ocular Inflammation • Ophthalmology • Retinal Disorders • Retinal Vein Occlusion • Wet Age-related Macular Degeneration

Safety and Efficacy of AM712 in Patients with NAMD (clinicaltrials.gov) - P1 | N=21 | Completed | Sponsor: AffaMed Therapeutics Limited | Recruiting ➔ Completed | Trial completion date: Jun 2024 ➔ Nov 2024 | Trial primary completion date: Jun 2024 ➔ Nov 2024

Trial completion • Trial completion date • Trial primary completion date • Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders • Wet Age-related Macular Degeneration

A Study of ASKG712 in Patients With Diabetic Macular Edema (clinicaltrials.gov) - P1 | N=26 | Not yet recruiting | Sponsor: AskGene Pharma, Inc.

New P1 trial • Diabetic Macular Edema • Ophthalmology

A Study of ASKG712 in Patients With Neovascular Age-Related Macular Degeneration (clinicaltrials.gov) - P1 | N=36 | Recruiting | Sponsor: AskGene Pharma, Inc. | Not yet recruiting ➔ Recruiting | Initiation date: Jul 2022 ➔ Feb 2023

Enrollment open • Trial initiation date • Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders • Wet Age-related Macular Degeneration

A Study of ASKG712 in Patients With Neovascular Age-Related Macular Degeneration (clinicaltrials.gov) - P1 | N=36 | Not yet recruiting | Sponsor: AskGene Pharma, Inc.

New P1 trial • Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders • Wet Age-related Macular Degeneration

Safety and Efficacy of AM712 in Patients With nAMD (clinicaltrials.gov) - P1 | N=24 | Recruiting | Sponsor: AffaMed Therapeutics (US) Inc. | Not yet recruiting ➔ Recruiting

Enrollment open • Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders • Wet Age-related Macular Degeneration

Safety and Efficacy of AM712 in Patients With nAMD (clinicaltrials.gov) - P1 | N=24 | Not yet recruiting | Sponsor: AffaMed Therapeutics (US) Inc.

New P1 trial • Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders • Wet Age-related Macular Degeneration