afacifenacin fumarate (SMP-986) / Sumitomo Pharma, Nippon Shinyaku - LARVOL DELTA

Drugs Currently Undergoing Preclinical or Clinical Trials for the Treatment of Overactive Bladder: A Review. (PubMed, Curr Ther Res Clin Exp) - "These are drugs acting on the autonomic nerve supply to the detrusor muscle of the urinary bladder that include the anticholinergics tarafenacin and afacifenacin and the β adrenoceptor agonists solabegron and ritobegron; drugs acting on ion channels in the detrusor muscle (eg, potassium channel openers and calcium channel blockers), drugs acting on cellular enzymes like phosphodiesterase-5 inhibitors and Rho kinase inhibitors, and drugs acting on miscellaneous targets (eg, pregabalin and trimetazidine). (Curr Ther Res Clin Exp. 2022; 83:XXX-XXX)."

Journal • Preclinical • Review • Overactive Bladder