The birth of a new ex-vivo haemostasis model (ISTH 2026) - May 25, 2026 - Abstract #PB2456; Pres time: Jul 13, 2026; 01:45 PM - 02:45 PM; Location: Exhibition Hall- Poster Area; "Haemostasis was assessed ex-vivo in placental vessels perfused in-situ with donor blood, by measuring bleeding time following needlestick injuries (300µm) in the presence of rivaroxaban, vorapaxar, cangrelor or Glenzocimab. Conclusions Placental vessels offer a viable option to develop ex-vivo models of human thrombosis and haemostasis, with the potential to reduce animal usage and improve translation of results. DOI*10.1016/j.rpth.2026.105196"
Preclinical • Cardiovascular • Hematological Disorders • Thrombosis
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Azziza Zaabalawi 1; Brenda Ghosh 2; May Azzawi 1; Paul Brownbill 2; Sarah Jones 1
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