Levofloxacin Inhalation Solution: Superior Efficacy and Minimized Hepatotoxicity Against Chronic Pseudomonas Aeruginosa-Induced Pulmonary Infection. (PubMed, AAPS PharmSciTech) - Mar 17, 2026 - "Additionally, LIS avoided the hepatotoxicity associated with systemic levofloxacin exposure, as evidenced by stable liver enzyme levels and normal hepatic pathology. This established LIS offered a promising therapeutic candidate for refractory PA-induced pulmonary infections and a valuable framework for advanced antimicrobial inhalation therapy development."
Journal • Infectious Disease • Respiratory Diseases
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Chuanbin Wu; Jingna Xu; Langui Xie; Min Yang; Mingmei Wang; Shihao Cai; Xia Zhao; Xiao Yue; Xuejuan Zhang; Yue Zhou; Yuqi Sun
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