Surfactant therapy in neonatal care: advances, challenges, and practical considerations. (PubMed, Eur J Pediatr) - Feb 21, 2026 - "Emerging innovations include SP-B/SP-C analog formulations and recombinant SP-D-based adjunct approaches, although several strategies remain investigational and require further validation. Key ongoing challenges include optimizing dosing and delivery efficiency, harmonizing monitoring and outcome definitions across studies, and improving cost-effectiveness. Overall, this review provides an updated critical perspective on surfactant therapy and future directions toward more individualized neonatal respiratory care."
Journal • Review • Acute Respiratory Distress Syndrome • Immunology • Respiratory Diseases
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Asghar Marzban; Pouya Karami Dehkordi
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