Lupkynis (voclosporin) - Aurinia Pharma, Otsuka
Gut microbiota and metabolic modulation by supplementation of polysaccharide-producing Bacillus licheniformis from Tibetan Yaks: A comprehensive multi-omics analysis. (PubMed, Int J Biol Macromol) - Nov 6, 2023 - "Nine metabolites, including olprinone, pyruvic acid, and 2-methyl-3-oxopropanoate, were upregulated, while eleven, including defoslimod and voclosporin, were down-regulated, shedding light on phenylpropanoid biosynthesis, tricarboxylic acid cycle (TCA cycle), and the glucagon signaling pathway. This comprehensive multi-omics analysis offers compelling insights into the potential of B. licheniformis as a dietary polysaccharide supplement for gut health and host metabolism, promising significant implications for gut-related issues." 
Journal
http://www.ncbi.nlm.nih.gov/pubmed/37926310
 
Chuxian Quan; Jiakui Li; Kewei Li; Mudassar Iqbal; Muhammad Fakhar-E-Alam Kulyar; Saisai Gong; Shah Nawaz; Shimeng Zhou; Zhibo Zeng
 
Nov 6, 2023
 
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