A Case of Rituximab Rescue Therapy in Class V Lupus Nephritis with Severe Hematological Manifestations (NKF-SCM 2023) - Feb 18, 2023 - Abstract #145; Location: Exhibit Hall; "She maintained remission with urine protein-to-creatinine ratio (UPCR) 0.22 g/g while on mycophenolate and cyclosporine...She received treatment with IVIG and dexamethasone with improvement in platelets to >100,000...The patient was subsequently started on Voclosporin, MMF and corticosteroids based on the AURORA 1 trial.Conclusion We presented a case of a female with juvenile onset of SLE and LN V with hematological flare manifestations...ITP is the most common cause of severe thrombocytopenia in SLE but other causes should be considered. This case report highlights the advantage of multidisciplinary care in the management of LN flare with severe extrarenal manifestations and the use of rituximab as rescue therapy."
Clinical • Anemia • Cardiovascular • Glomerulonephritis • Hematological Disorders • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology • Rheumatology • Systemic Lupus Erythematosus • Thrombocytopenia • Thrombocytopenic Purpura
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Rafael Sancillo1,2; Jesse Wickham1,2; David DeMasters1
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