Steroid-sensitive and Frequently Relapsing Lupus Podocytopathy: a role for Obinutuzumab (NKF-SCM 2026) - Mar 6, 2026 - Abstract #G-133; "However, she developed a steroid-senstive, frequently relapsing course with relapses occuring at prednisone below 15mg/day. Multiple steroid-sparing stragies failed, including higher dose mycophenolic acid, voclosporin, and cyclophosphamide...This case also illustrates development of anti-rituximab antibodies as a cause of early B cell repopulation and disease relapse; urinary loss of rituximab due to heavy proteinuria may have also contributed to rituximab failure. CONCLUSION Obinutuzumab may be a promising steroid-sparing treatment for steroid-sensitive, frequently relapsing lupus podocytopathy."
Glomerulonephritis • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology • Renal Disease
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Omid Vadpey; Anatoly Urisman; Sarah French; Christopher Carlos; Raymond Hsu
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