Lupkynis (voclosporin) - Aurinia Pharma
Lenvima (lenvatinib) - Eisai, Merck (MSD)
Drug-related proteinuria: a vigilance analysis based on the FAERS database. (PubMed, Braz J Med Biol Res) - Mar 4, 2026 - "Among these, 21 drugs demonstrated statistically significant associations with proteinuria based on multivariate logistic regression, with the highest signals observed for voclosporin (ROR: 63.57) and lenvatinib (ROR: 41.01). These findings underscore the need for early and long-term renal monitoring depending on drug category. Prompt assessment of nephrotoxicity risk is essential during the initial phase of medication, hence offering a more precise foundation for drug screening and optimization." 
Journal • Renal Disease
http://www.ncbi.nlm.nih.gov/pubmed/41779560
 
Hongbing Wang; Junying Zhang; Linjian Zhou; Yi Nie; Zhixiang Mao
 
Mar 4, 2026
 
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