Lupkynis (voclosporin) - Aurinia Pharma
cyclosporin A microemulsion - Generic mfg.
Two-Hour Post-dose (C2)-Monitored Cyclosporine Microemulsion as a Practical Alternative to Voclosporin in Mixed Class IV/V Lupus Nephritis: A Case Report. (PubMed, Cureus) - Mar 2, 2026 - "This case demonstrates that individualized C2-guided CsA-ME dosing was associated with marked proteinuria reduction and preservation of kidney function. The observed response suggests pharmacodynamic effects that may overlap with those reported for voclosporin, within a fully oral, non-depletive regimen selected to mitigate treatment-related toxicity from cytotoxic therapy after shared decision-making with the patient." 
Journal • Chronic Kidney Disease • Glomerulonephritis • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology • Renal Disease • Systemic Lupus Erythematosus
http://www.ncbi.nlm.nih.gov/pubmed/41769630
 
Divya Akella; Virin Ramoutar
 
Mar 2, 2026
 
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