Comparative risk of arrhythmias associated with systemic antifungal agents: a disproportionality analysis of the FAERS database. (PubMed, Front Pharmacol) - Jun 12, 2026 - "The ranking of the number of positive signals across four types of SMQs was as follows: Itraconazole (4), Fluconazole (3), Posaconazole (3), Voriconazole (2), Caspofungin (1), Amphotericin B (1), Flucytosine (0), Isavuconazole (0), Micafungin (0). Itraconazole, fluconazole, and posaconazole demonstrated stronger arrhythmogenic risks, whereas micafungin, flucytosine, and isavuconazole showed negative signals across all four SMQs. In clinical practice, individual patient risk should be comprehensively assessed to guide personalized drug selection."
Journal • Cardiovascular
|
|
Hao Li; Kai Liu; Lingti Kong; Xiaohu Yang
|