Invasive pericardial and pulmonary aspergillosis by uncommon Aspergillus species in anti-interferon-γ autoantibody-associated immunodeficiency: a case report. (PubMed, Front Med (Lausanne)) - May 4, 2026 - "Despite sequential antifungal therapy with voriconazole, isavuconazole, and amphotericin B, the patient developed progressive multifocal infection, including an abdominal wall abscess and mediastinal infection caused by Aspergillus siamensis, and ultimately died of multiple organ failure. This case highlights the diagnostic challenges and poor prognosis associated with this rare immunodeficiency syndrome and emphasizes the importance of early recognition, precise pathogen identification, and consideration of immunomodulatory therapy."
Journal • Infectious Disease • Inflammation • Pulmonary Disease • Respiratory Diseases • IFNG
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Cheng Li; Guixin Zhang; Junyuan Tang; Lin Chen; Wenbo Jiang; Xuejiao Sun; Yuhong Liu; Yunhong Li; Yunying Weng; Zhijuan Luo
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