Chronic Neutrophilic Leukemia With the CSF3R T618I Mutation: Diagnostic and Therapeutic Challenges in a BCR::ABL1-Negative Myeloproliferative Neoplasm (SOHO 2026) - Sep 1, 2026 - Abstract #MPN-040; "The patient was initially started on hydroxyurea, but it was halted due to worsening anemia. Maxson et al reported considerable clinical improvement with ruxolitinib in a patient harboring this mutation.1 This case highlights the importance of comprehensive molecular testing in assessing persistent neutrophilia and emphasizes the diagnostic and therapeutic significance of the CSF3R T618I mutation. Ongoing clinical trials and consensus-based guidelines are needed to advance the management strategies for this rare hematological cancer."
Chronic Neutrophilic Leukemia • Hematological Malignancies • Leukemia • Myeloproliferative Neoplasm • Oncology • ABL1 • BCR • CALR • CSF3R • MPL
|
|
Hafiza Akhtar MD 1; Ifunaya Ekechukwu MD 1; Sameer Bhimani MD 1; Si-Yuen Moy MD 2
|