Isolated Gastric Variceal Hemorrhage From Sinistral Portal Hypertension in JAK2 V617F-Positive Myeloproliferative Neoplasm (ACG 2026) - Aug 29, 2026 - Abstract #P5564; Pres time: Oct 13, 2026; 10:30 AM - 04:00 PM; Location: Exhibit Halls A - D (Level 3); "Case Description/ A 48-year-old male with JAK2 V617F-positive MPN and chronic portal and splenic vein thrombosis, noncompliant with hydroxyurea and warfarin therapy, presented with 1 episode of hematemesis...He was resuscitated with vasopressors, octreotide, and pantoprazole infusion, and treated with rasburicase for TLS...He was ultimately transitioned to ruxolitinib as outpatient therapy, with normalization of counts and resolution of bleeding at follow-up...Figure: Figure 2. Esophagogastroduodenoscopy showing extensive isolated gastric varices (IGV1 and IGV2) and an actively bleeding, ulcerated varix (image 14), which was clipped endoscopically."
Cardiovascular • Gastroenterology • Gastrointestinal Disorder • Hematological Disorders • Hepatology • Hypertension • Myeloproliferative Neoplasm • Portal Hypertension • Thrombocytosis • Thrombosis • Varicose Veins • JAK2
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Ritwik Dey MD 1; Virali Gulla MD 1; Souvik Saha MD 2; Alejandro Robles MD 1; Jesus Gomez MD 3
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