Development of electrochemical nanoprobe for real-time intracellular measurements of Fe2+ during ferroptosis. (PubMed, Microsyst Nanoeng) - Jul 8, 2025 - "We use the nanoprobes to evaluate the intracellular change of Fe2+ in MCF-7 breast cancer cells during erastin-induced ferroptosis. We observe a significant increase in intracellular Fe2+ levels in MCF-7 cells undergoing ferroptosis, accompanied by a notable rise in ROS levels. These findings underscore the potential of this nanoprobe to enhance our understanding of the mechanism of ferroptosis in tumor development and as a potential treatment target."
Journal • Breast Cancer • Oncology • Solid Tumor
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Chengzhi Hu; Hongri Gu; Lingqian Chang; Ming Yang; Muyang Ruan; Weikang Hu; Xinhao Li; Yanmei Ma
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