Hypoxia-Inducible Factor HIF1α Regulates the Expression of SLC7A1 to Mediate Erastin-Induced Ferroptosis in Cervical Cancer Cells.

erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys

Hypoxia-Inducible Factor HIF1α Regulates the Expression of SLC7A1 to Mediate Erastin-Induced Ferroptosis in Cervical Cancer Cells. (PubMed, J Gene Med) - Jul 7, 2025 - "HIF1α regulates the expression of YTHDF1, thereby enhancing the m6A modification level of SLC7A1, promoting its expression, and ultimately inhibiting Erastin-induced ferroptosis in CaCx cells."
Journal • Cervical Cancer • Oncology • Solid Tumor • HIF1A • YTHDF1

http://www.ncbi.nlm.nih.gov/pubmed/40618777

Yan Lei; Yanling Li; Yanqing Huang

Jul 7, 2025