Taohong Siwu Decoction Modulates Glutathione Metabolism to Suppress Hepatocyte Ferroptosis and Demonstrates Anti-Fibrotic Effects in the Liver. (PubMed, J Ethnopharmacol) - May 26, 2025 - "THSW represents a novel therapeutic effect on hepatic fibrosis in mice, accompanied by inhibiting hepatocyte ferroptosis. Mechanically, THSW may regulate the glutathione metabolic pathway and TFRC expression through its main ingredients, such as amygdalin, hydroxysafflor yellow A, paeoniflorin, and albiflorin, thereby inhibiting hepatocyte ferroptosis."
Journal • Fibrosis • Hepatology • Immunology • Inflammation • GPX4 • GSTM1 • KEAP1 • SLC7A11
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Dingqi Zhang; Fangming Yang; Shenglan Qi; Shengsheng Li; Siqi Gao; Suping Ma; Yu Zhang; Zhenyi Niu; Zhongping Duan; Zhun Xiao
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