Lung microbiota metabolite L-malic acid attenuates the airway inflammation in asthma by inhibiting ferroptosis. (PubMed, Toxicol Appl Pharmacol) - May 18, 2025 - "However, the introduction of ferroptosis inducers, such as Erastin, was observed to negate the beneficial effect of butyrate. In summary, this research implies that the respiratory microbiota metabolite L-malic acid lessens airway inflammation in asthma by inhibiting ferroptosis, offering a potential approach for managing asthma."
Journal • Asthma • Immunology • Inflammation • Metabolic Disorders • Pulmonary Disease • Respiratory Diseases • GPX4
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Cuiping Ye; Danhui Huang; Hangming Dong; Haohua Huang; Lanhe Chu; Lingyan Xie; Lishan Lin; Shaoxi Cai; Xiaojing Meng; Yi Huang; Yujie Qiao
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