Schisandrin B ameliorates Alzheimer's disease by suppressing neuronal ferroptosis and ensuing microglia M1 polarization. (PubMed, Phytomedicine) - May 19, 2025 - "Sch B modulates the GSK3β/Nrf2/GPX4 pathway in conjunction with FSP1 to inhibit neuronal ferroptosis and the subsequent microglial M1 polarization mediated by neuronal ferroptosis, thereby improving cognitive impairment and pathological damage in AD." Journal • Alzheimer's Disease • CNS Disorders • Cognitive Disorders • AIFM2 • GPX4 • TNFA
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Meiying Song; Shanshan Zhang; Tao Ding; Xiang Fan; Yongshi Wu; Zhu Li
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