SLC7A9 suppression increases chemosensitivity by inducing ferroptosis via inhibiting cystine transportation in gastric cancer (IGCC 2025) - May 17, 2025 - Abstract #P498; Pres time: May 8, 2025; "In models, SLC7A9 suppression or inhibition with erastin showed therapeutic potential... SLC7A9 expression was up-regulated in gastric cancer tumor tissues and negatively correlated with overall survival. SLC7A9 conferred resistance to ferroptosis in gastric cancer cells. P53 acted as a repressive transcription factor regulating SLC7A9 expression in gastric cancer."
Gastric Cancer • Oncology • Solid Tumor • GPX4
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Li J1; Feng H1; Zhu Z1; Liu B1
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