Identification and functional characterization of prognosis-related ferroptosis-associated lncRNAs in colorectal cancer. (PubMed, Front Immunol) - May 14, 2025 - "Further functional assays included ferroptosis induction with RSL3 and Erastin, cell viability assessments, immunofluorescence staining for lipid peroxidation, and Western blot analysis of ferroptosis-related proteins. DEFRlncRNAs, particularly Lnc-LSS-1 and Lnc-PEX11G-4, play crucial roles in regulating ferroptosis in CRC. These lncRNAs have potential as novel prognostic markers and therapeutic targets, providing valuable insights for personalized CRC treatment strategies."
Biomarker • Journal • Colorectal Cancer • Oncology • Solid Tumor • GPX4
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Jian Wang; Jiasheng Xu; Jinjie He; Xiaoxu Ge; Yucheng Qian
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