erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys
Male-specific lethal 1 (MSL1) promotes Erastin-induced ferroptosis in colon cancer cells by regulating the KCTD12-SLC7A11 axis. (PubMed, Cell Death Dis) - Apr 13, 2025 - "Consistently, Erastin-induced changes in ROS, GSH, and MDA levels were regulated by this axis, highlighting its role in ferroptosis. These findings offer potential therapeutic targets and a theoretical foundation for colon cancer treatment." 
Journal • Colon Cancer • Colorectal Cancer • Oncology • Solid Tumor • KCTD12 • SLC7A11
http://www.ncbi.nlm.nih.gov/pubmed/40221412
 
Bing Liang; Chengyu Cai; Jingji Jin; Lifu Luo; Nan Jiang; Qingzhi Zhao; Shijiao Dong; Xueli Cui; Yong Wang
 
Apr 13, 2025
 
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