Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway. (PubMed, Phytomedicine) - Apr 12, 2025 - "These results establish BCA as a promising natural compound for UC treatment, offering a novel therapeutic strategy by specifically targeting ferroptosis and its associated molecular pathways, thereby addressing key gaps in current UC management and advancing potential clinical applications."
Journal • Gastroenterology • Gastrointestinal Disorder • Immunology • Inflammation • Inflammatory Bowel Disease • Oncology • Stress Ulcer • Ulcerative Colitis • GPX4
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Beiying Deng; Haodong He; Jiao Li; Jingjing Ma; Jixiang Zhang; Kunpeng Wang; Miao Xu; Pengzhan He; Weiguo Dong; Yinghui Liu
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