The molecular mechanism of ferroptosis in the Pacific oyster Crassostrea gigas under Erastin treatment or high temperature stress. (PubMed, Dev Comp Immunol) - Apr 5, 2025 - "Those of genes involved in impairing the antioxidation system, genes involved in inhibiting the iron metabolism, as well as genes involved in reducing the lipid peroxidation all increased significantly under Erastin treatment or high temperature stress. These results indicated that Erastin could activate the three key ferroptotic signaling pathways in oyster and the activation mechanism of ferroptosis in oyster under high temperature stress was similar with that under Erastin treatment."
Journal • Musculoskeletal Diseases • Orthopedics
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Jiejie Sun; Jinyuan Leng; Lingling Wang; Linsheng Song; Zhicheng Guo
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