Theabrownins improve burn-induced kidney injury by increasing the levels of guanidinoacetic acid and fumaric acid. (PubMed, Phytomedicine) - Mar 17, 2025 - "Burns induce inflammation and kidney damage by upregulating the apoptosis and ferroptosis pathways in renal tissue. TBs alleviate burn-induced renal apoptosis and ferroptosis by increasing the levels of GAA and FA in the kidneys, thereby ameliorating kidney damage. This study innovatively and systematically evaluated the ability of TBs to ameliorate burn-induced kidney injury and, for the first time, identified the potential mechanism by which TBs ameliorate burn-induced kidney damage by increasing the levels of the metabolites GAA and FA in the kidneys."
Journal • Acute Kidney Injury • Inflammation • Nephrology • Renal Disease • Thermal Injury
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Changshun Han; Chengyong He; Hongbin Zhong; Jiancheng Huang; Jiyi Huang; Lixin Liao; Tianyun Peng; Xiaoyan Ding; You Gao; Zhiyuan Chen
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