Vagus nerve stimulation alleviates myocardial injury following hepatic ischemia-reperfusion in rats by inhibiting ferroptosis via the activation of the SLC7A11/GPX4 axis.

erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys

Vagus nerve stimulation alleviates myocardial injury following hepatic ischemia-reperfusion in rats by inhibiting ferroptosis via the activation of the SLC7A11/GPX4 axis. (PubMed, Eur J Med Res) - Mar 13, 2025 - "VNS protects against myocardial injury from hepatic ischemia-reperfusion, likely by inhibiting oxidative stress and ferroptosis through activation of the SLC7A11/GPX4 axis."
Journal • Preclinical • Cardiovascular • Hematological Disorders • Hepatology • Liver Failure • Reperfusion Injury • GPX4 • SLC7A11 • TNNI3

http://www.ncbi.nlm.nih.gov/pubmed/40075496

Haiyan Wang; Jinping Wang; Po Zhang; Yuanjing Qin

Mar 13, 2025