Caveolin-1 protects against liver injury and lipid accumulation in alcoholic fatty liver via ferroptosis resistance. (PubMed, Mol Immunol) - Mar 13, 2025 - "Ferroptosis agonist (Erastin) treatment abrogated CAV1 plasmid-mediated ferroptosis resistance and steatosis alleviation. Collectively, the results revealed a crucial role of CAV1 in preventing hepatic steatosis and ferroptosis in alcohol-induced liver injury, which may identify potential targets for the treatment of AFL."
Journal • Acute Myelogenous Leukemia • Hematological Disorders • Hepatology • Liver Failure • Metabolic Dysfunction-Associated Steatotic Liver Disease • ACSL4 • CAV1 • GPX4 • SLC7A11
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Chengmu Hu; Jianjun Liu; Liang Shan; Ning Guo; Weiju Xue; Xing Fang; Xiuzhen Liu; Yong Wang; Yuquan Sun; Zhengsheng Zhang
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