Ferritin1-mediated ferroptosis participates in granular acini degeneration of Haemaphysalis longicornis salivary glands. (PubMed, Ticks Tick Borne Dis) - Mar 11, 2025 - "In vitro culture of H. longicornis salivary glands showed that erastin promotes ferroptosis, while ferrostatin-1 blocks this process...In conclusion, we demonstrated that HlFer1-induced ferroptosis is a key molecular mechanism underlying the salivary gland granular acini degeneration of H. longicornis. Our findings are important for developing novel preventive measures against H. longicornis as a disease vector."
Journal • GPX4 • HMGB1
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Dongqi Yuan; Houshuang Zhang; Jie Cao; Jinlin Zhou; Songqin Chen; Yanan Wang; Yongzhi Zhou
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