Ferroptosis in plant immunity. (PubMed, Plant Commun) - Mar 9, 2025 - "The small-molecule inducer erastin triggers iron-dependent lipid ROS accumulation and glutathione depletion, leading to HR cell death in plant immunity...These breakthroughs suggest a potential role of Ca2+ signaling in ferroptosis and its coordination with iron and ROS signaling in plant immunity. In this review, we highlight the essential roles of calcium, iron, and ROS signaling in ferroptosis during plant immunity and discuss advances in the understanding of how Ca2+-mediated ferroptotic cell death orchestrates effective plant immune responses against invading pathogens."
Journal • Review • Infectious Disease • NR3C1
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Byung Kook Hwang; Nam-Soo Jwa
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