Dicoumarol sensitizes hepatocellular carcinoma cells to ferroptosis induced by imidazole ketone erastin. (PubMed, Front Immunol) - Feb 26, 2025 - "In conclusion, our findings demonstrate that DIC sensitized HCC cells to IKE-induced ferroptosis in HCC. Moreover, the identification of potential drugs that enhance the susceptibility of HCC cells to ferroptosis could provide novel therapeutic strategies for the treatment of HCC."
IO biomarker • Journal • Hepatocellular Cancer • Oncology • Solid Tumor • NQO1 • SLC7A11
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Fei Huo; Gang Zhou; Jiali Yang; Jialu Hou; Jiao Wu; Peng Lin; Ruibin Yang; Shijie Wang; Tixin Han; Xiaohang Xie; Yaxin Ding; Yifei Qin; Yinuo Zhang; Zhi-Nan Chen; Zhuan Feng; Ziwei Yang
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