erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys
Screening of Regulatory mRNAs and miRNAs that Suppress Staphylococcus aureus Proliferation via Macrophage Ferroptosis. (PubMed, Curr Microbiol) - Feb 11, 2025 - "The study findings revealed that erastin concentrations (< 20 μM), which do not have an impact on macrophage proliferation, can effectively impede the proliferation of S. aureus within macrophages...Notably, our study has identified GM867, GPR176, mmu-miR-6935-5p, and mmu-miR-7082-3p as key regulators involved in this process. These findings highlight the potential of targeting these four molecules for HDT, offering novel ways to combat drug-resistant S. aureus infection." 
Journal • Infectious Disease • GPR176
http://www.ncbi.nlm.nih.gov/pubmed/39932559
 
Anlong Li; Dan He; Danyang Yang; Jiajia Bao; Lei Xu; Lili Wang; Lin Liu; Qinya Yang; Sifei He; Sijia Gao; Xintong He; Yulian Xu
 
Feb 11, 2025
 
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