Aucubin Promotes BMSCs Proliferation and Differentiation of Postmenopausal Osteoporosis Patients by Regulating Ferroptosis and BMP2 Signalling. (PubMed, J Cell Mol Med) - Jan 18, 2025 - "The results indicated that aucubin significantly inhibited ROS generation and oxidative stress induced by erastin and protected against ferroptosis in hBMSCs. Additionally, aucubin facilitated osteogenic differentiation of hBMSCs by activating the BMP2/SMADs pathway and attenuated the progression of osteoporosis in OVX rats, suggesting a potential therapeutic benefit for postmenopausal osteoporosis (PMOP)."
Journal • Metabolic Disorders • Osteoporosis • Rheumatology • BMP2
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Congcong Yu; Huan Yang; Jianhua Zhang; Long Liang; Meichun Han; PengYu Chen; Renfu Quan; Rongtai Sun; Shasha Yao; Tianyuan Gu; Ting Jiang; Xing Zhao; Yang Zheng; Yangyang Ding
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