Absence of Cysteine and Iron Chelation Induces Ferroptosis in Triple-Negative Breast Cancer Cells. (PubMed, Breast Cancer (Auckl)) - Jan 18, 2025 - "On the contrary, cells when treated with deferoxamine along with erastin (ferroptosis-inducing drug), showed an increase in cell iron content was observed, later inducing ferroptosis. Our results show an alternative function of cysteine and deferoxamine, one regulating lipid droplets and the other inducing ferroptosis, although an inhibitor of the same, respectively."
Journal • Breast Cancer • Oncology • Solid Tumor • Triple Negative Breast Cancer
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Junjeong Choi; Manvi Agarwal Neeraj
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