EGCG activates Keap1/P62/Nrf2 pathway, inhibits iron deposition and apoptosis in rats with cerebral hemorrhage. (PubMed, Sci Rep) - Dec 29, 2024 - "The neurons were pre-treated with EGCG before being exposed to Erastin and RSL3 to induce iron death. Through the activation of the Keap1/P62/Nrf2 pathway, EGCG inhibits inflammation, oxidative stress and iron deposition in rats with cerebral hemorrhage. EGCG inhibits oxidative stress, iron deposition and apoptosis in rats with ICH by activating Keap1/P62/Nrf2 pathway."
Journal • Preclinical • Cerebral Hemorrhage • CNS Disorders • Hematological Disorders • Inflammation • Vascular Neurology • GPX4
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Aobo Zhang; Dongsheng Lv; Liang Hao; Liqiang Liu; Lulu Cong; Zhimin Sun
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