Study on the role of SLC7A11-mediated amino acid metabolism dysregulation in the pathogenesis of psoriasis (PsoriasisG2C 2024) - Dec 24, 2024 - Abstract #P81; "We used the imiquimod (IMQ) model to induce skin inflammation and tested the effect of the SLC7A11 inhibitor, imidazole ketone erastin. Targeting SLC7A11 could be a promising immunosuppressive strategy for controlling psoriatic inflammation. This study provides new insights into the metabolic aspects of psoriasis and highlights the potential of SLC7A11 as a therapeutic target."
Dermatitis • Dermatology • Immunology • Inflammation • Metabolic Disorders • Psoriasis • CCL20 • CXCL5 • SLC7A11
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Yuanyuan Wang, 1,2; Xilin Zhang1,2; Yuling Shi1,2
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