Dysregulation of Iron Homeostasis Mediated by FTH Increases Ferroptosis Sensitivity in TP53-Mutant Glioblastoma. (PubMed, Neurosci Bull) - Dec 12, 2024 - "Interestingly, we found that Erastin combined with FAC treatment significantly increased ferroptosis. These findings provide new insights for drug development and therapeutic modalities for GBM patients with TP53 mutations from iron metabolism perspectives."
Journal • Brain Cancer • CNS Tumor • Glioblastoma • Oncology • Solid Tumor • Targeted Protein Degradation • TP53 • UBR5
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Hong Jiang; Hongliang Zhang; Jiangang Li; Lei Cheng; Peng Lun; Qian Jiao; Xi Chen; Xixun Du; Xuejie Huan; Zhaobin Chu
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