CKS2 induces autophagy-mediated glutathione metabolic reprogramming to facilitate ferroptosis resistance in colon cancer. (PubMed, Mol Med) - Nov 18, 2024 - "CKS2 suppresses ferroptosis in CC by modulating GSH metabolism in both in vitro and in vivo settings. These findings offer new insights into targeting CKS2 for CC treatment and shed light on the mechanism of ferroptosis in CC."
Journal • Colon Cancer • Colorectal Cancer • Oncology • Solid Tumor • CKS2 • GPX4
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Chengfeng Fang; Dinghai Luo; Jiaju Han; Leilei Yang; Lingyan Shen; Ruili Zhang; ShenKang Zhou; Yan Chen; Yufeng Ren; Zaiping Yang
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