The Role of STEAP3 in Pathogenesis of Gliomas: An Independent Prognostic Factor and Regulator of Ferroptosis. (PubMed, Ann Clin Lab Sci) - Nov 16, 2024 - "STEAP3 serves as an independent biomarker for glioma prognosis with significant diagnostic value. High STEAP3 expression was correlated with poor overall outcomes of glioma patients. Knockdown of STEAP3 significantly suppressed the proliferation of glioma cells and increased erastin-induced ferroptosis via Nrf2/GPX4 pathway." Biomarker • Journal • Brain Cancer • CNS Tumor • Glioblastoma • Glioma • Oncology • Solid Tumor • GPX4 • STEAP1 • STEAP3
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Fang Ling; Hong Cheng; Jing Wang; Xiaoli Hou; Yasen Cao; Yingjie Zhao; Yixia Wang
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