Emerging insights into ferroptosis in cholangiocarcinoma (Review). (PubMed, Oncol Lett) - Nov 1, 2024 - "Inhibitors of ferroptosis include ferrostatin-1, liproxstatin-1, vitamin E and coenzyme Q10. By contrast, compounds such as erastin, RSL3 and FIN56 have been identified as inducers of ferroptosis...The present review focused on molecular targets such as p53 and ACSL4, the process of targeted medications in combination with PDT in CCA and the pathways of lipid peroxidation, the Xc-system and GSH-GPX4 in ferroptosis. The present review thus offered novel perspectives to improve the current understanding of CCA."
Journal • Review • Biliary Cancer • Cholangiocarcinoma • Gastrointestinal Cancer • Metabolic Disorders • Oncology • Solid Tumor • ACSL4 • GPX4
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Jing He; Miao Zhang; Xiaoyue Zhao; Xin Li; Xuewei Zhuang
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