PRMT4 Reduced Erastin-Induced Ferroptosis in Nasopharyngeal Carcinoma Cisplatin-Resistant Cells by Nrf2/GPX4 Pathway. (PubMed, J Environ Pathol Toxicol Oncol) - Oct 27, 2024 - "Methylation increased PRMT4 DNA stability. Collectively, our data reveal that PRMT4 reduced erastin-induced ferroptosis in NPC cisplatin-resistant cells by Nrf2/GPX4 pathway, suggesting that targeting PRMT4 may present as a potential strategy against the development of NPC."
Journal • Nasopharyngeal Carcinoma • Oncology • Solid Tumor • Targeted Protein Degradation • GPX4
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Fang Yang; Hong Wu; Xiaoping Pu; Xiaoyan Liu
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