Synergistic ferroptosis in triple-negative breast cancer cells: Paclitaxel in combination with Erastin induced oxidative stress and Ferroportin-1 modulation in MDA-MB-231 cells. (PubMed, Naunyn Schmiedebergs Arch Pharmacol) - Oct 11, 2024 - "The expression of ferroptosis-regulating proteins was significantly downregulated. The findings showed that the Paclitaxel-Erastin combination synergistically contributed to the accumulation of lipid reactive oxygen species and induced the ferroptotic cell death pathway in breast cancer cells."
Combination therapy • Journal • Breast Cancer • Oncology • Solid Tumor • Triple Negative Breast Cancer
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Erva Ozkan; Filiz Bakar-Ates
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