Inhibition of FABP4 Ameliorates IL-13-Induced Inflammatory Response and Barrier Dysfunction in Nasal Mucosal Epithelial Cells through the Regulation of Ferroptosis. (PubMed, Cell Biochem Biophys) - Sep 22, 2024 - "Nevertheless, erastin pre-treatment partially counteracted the protective role of FABP4 depletion against inflammation, mucus production and barrier dysfunction in IL-13-treated hNECs. In summary, FABP4 deficiency ameliorated IL-13-induced inflammatory response and barrier dysfunction in nasal mucosal epithelial cells through the regulation of ferroptosis."
Journal • Allergic Rhinitis • Immunology • Inflammation • Otorhinolaryngology • FABP4 • IL13 • MUC5AC • TJP1
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