Laser-responsive erastin-loaded chondroitin sulfate nanomedicine targeting CD44 and system xc- in liver cancer: A non-ferroptotic approach. (PubMed, J Control Release) - Sep 21, 2024 - "Combined with laser irradiation, ECINs significantly decreased tumor size (2.6-fold, compared to free erastin; 2.4-fold, compared to ECINs without laser irradiation) with minimal systemic toxicity. This study highlights ECINs as a dual-modality approach for liver cancer treatment, demonstrating significant efficacy against tumors overexpressing CD44 and system xc-."
Journal • Gastrointestinal Cancer • Hepatocellular Cancer • Hepatology • Liver Cancer • Oncology • Solid Tumor • CD44
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Dae-Duk Kim; Dong Hwan Lee; Dong Hyun Kim; Hyun Young Kim; Jae-Young Lee; Jang Mo Koo; Jang Su Jeon; Ji Hoon Yoo; Ji-Yoon Lee; Jieun Yu; Jong Chan Park; Keon Wook Kang; Min-Jun Baek; Sang Kyum Kim; Sang Min Lee; Seokjin Koh; So-Yeol Yoo; Soo Jin Oh; Wan Seob Shim
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