Hypoxia-induced BAP1 enhances erastin-induced ferroptosis in nasopharyngeal carcinoma by stabilizing H2A. (PubMed, Cancer Cell Int) - Sep 9, 2024 - "Hypoxia-induced BAP1 enhances erastin-induced ferroptosis in NPC by stabilizing H2A. Ferroptosis inducers targeting BAP1 may be an effective way to improve chemotherapy resistance in NPC, especially in the hypoxic microenvironment."
Journal • Head and Neck Cancer • Nasopharyngeal Carcinoma • Oncology • Solid Tumor • Squamous Cell Carcinoma • Squamous Cell Carcinoma of Head and Neck • Targeted Protein Degradation • BAP1 • HIF1A • SLC7A11
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Minlan Yang; Sa Wu; Weisong Cai; Xiaoping Ming; Xiong Chen; Xiuping Yang; Zehua Lin
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