erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys
Fluorescent probes for formaldehyde based on formaldehyde-promoted C-N cleavage of azanyl carbamates. (PubMed, Org Biomol Chem) - Aug 27, 2024 - "The 3-nitrophenylazanyl containing reactive group also functions as a fluorescence quenching group via a photo-induced electron transfer mechanism to generate turn-on fluorescence response upon reaction with FA. The probes were applied to explore FA level changes in erastin-induced ferroptosis, and it was found that the FA level increases intracellularly, but not in the endoplasmic reticulum, suggesting that the FA level increases in ferroptosis are not derived from lipid peroxidation." 
Journal
http://www.ncbi.nlm.nih.gov/pubmed/39189436
 
Huan Xu; Kaiyan Lou; Wanjin Xing; Wei Wang; Yang Li; Yulin Que
 
Aug 27, 2024
 
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