Clinical Characteristics Associated With Achieving â¥3 CSBMs/Week During Linaclotide Treatment in Adults With Chronic Idiopathic Constipation (ACG 2026) - Aug 29, 2026 - Abstract #P3083; Pres time: Oct 12, 2026; 10:30 AM - 04:15 PM; Location: Exhibit Halls A - D (Level 3); P3, P3b | "In the primary analysis, higher BL weekly CSBM rate showed the strongest association with achieving â¥3 CSBMs/week. Age and higher BMI demonstrated small positive associations with response, whereas other selected variables including antidepressant use GI history, treatment dose, BL pain, BL BSFS, and ethnicity were not significantly associated with response ( Table 2 ). In the female population, similar variables and associations were identified except use of antidepressants."
Clinical • Constipation • Gastroenterology • Gastrointestinal Disorder
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Kyle Staller MD MPH 1; Darren Brenner MD 2; Brian Lacy MD PhD 3; Gregory Sayuk MD MPH 4; Pierson Tu PharmD MBA 5; Fang Fang PhD 5; Jens J. Kort MD PhD 5; Sally Higgins PharmD 6; Danielle D'Achino PharmD 6; Anthony J. Lembo MD 7
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