Multi-omics Reveals Divergent Endothelial Molecular Responses to New and Old World Hantaviruses. (PubMed, bioRxiv) - Sep 25, 2026 - "Additionally, ANDV induced heightened activity of ERBB-family kinases, whose chemical inhibition by neratinib and afatinib reduced viral replication. Together, these data define species-specific responses in endothelial cells, identify druggable host targets, and reveal mechanisms with relevance to divergent vascular leakage symptomology."
Journal • Infectious Disease
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Andrea O Chan; Anne K Zaiss; Arjit Vijey Jeyachandran; Ashok Kumar; Brian Nguyen; Charles O Olwal; Declan M Winters; Evan T Wynn; Gustavo García; Immy A Ashley; Jocelyn J Ni; Justin Selby; Kareem Alba; Mehdi Bouhaddou; Nevan J Krogan; Pritha Sankar; Robert Damoiseaux; Sandra Papazian; Sara K Makanani; Shantanu Joshi; Shipra Sharma; Sophie F Blanc; Vaithilingaraja Arumugaswami; Valerie Vandersall; Vrithika Vaithi; Yennifer Delgado
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