TNKASE (tenecteplase) - Roche, Boehringer Ingelheim
Activase (alteplase) - Roche, Boehringer Ingelheim, Kyowa Kirin, Tanabe Pharma
Early Reperfusion in Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment. (PubMed, Stroke Vasc Interv Neurol) - Sep 9, 2026 - "In BAO treated within 4.5 hours of last known well, tenecteplase and alteplase produced comparable early reperfusion rates. Achieving ER did not modify the association between thrombolytic agent and good functional outcome, consistent with rapid thrombectomy in patients with no ER." 
Journal • Cardiovascular • CNS Disorders
http://www.ncbi.nlm.nih.gov/pubmed/42707799
 
Alexandra R Paul; Alhamza R Al-Bayati; Anoop Chinthala; Avi Gajjar; Bradley A Gross; Bradley N Bohnstedt; Christian T Sidebottom; Clemens M Schirmer; Dale Strong; Daniel Tonetti; David J Altschul; Dhrumhil Vaishnav; Dylan N Wolman; Gary Defilipp; Jan-Karl Burkhardt; Je Yeong Sone; Jeremy B Rhoten; Jiang Li; Justin Mascitelli; Krisztina Moldovan; Kwadwo Darko; Kyle W Scott; Mahesh V Jayaraman; Manisha Koneru; Matthew K Tobin; Matthew R Webb; Mohamed F Doheim; Nitin Goyal; Philipp Hendrix; Radmehr Torabi; Rahul R Karamchandani; Ramin Zand; Raul G Nogueira; Sasan Bahrami; Sumeet Multani; Thana Theofanis; Tyler M Bielinski; Visish Srinivasan; William J Ares
 
Sep 9, 2026
 
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